February 08, 2024 07:10 / Last edited by valriwirco1981 6 months ago
Indole-3-carbinol is useful for both men and women Downregulation of aromatase in men I3C and its constituent DIM, down-regulate the expression of aromatase, or CYP19, which is the protein responsible for converting testosterone into estrogen <2>. Decreasing the presence of aromatase can limit the amount of testosterone that is replaced by . ->
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Indole-3-carbinol (I3C), a natural phytochemical found in cruciferous vegetables (i. e. broccoli, cabbage or cauliflower), is considered a potential anticancer agent that prevents the development of certain types of tumors by activating tumor suppressor genes, genes involved in apoptosis and detoxification [ 2, 10 - 14 ].
This has saw it gain popularity in the bodybuilding world, but as yet, clinical human research has yet to provide conclusive, clear-cut, evidence of these effects. Reported Effects of Indole-3-Carbinol 1. Cancer Prevention. Indole-3-Carbinol has been purported as a chemo preventive agent, put simply, a substance that helps prevent cancer.
Indole-3-Carbinol promotes Bodybuilding, supports Weight Loss & Overall Performance. * Vegan / Vegetarian Friendly, Non-GMO, Egg Free, Dairy Free, Soy Free and Gluten Free. Contains No fillers, additives, preservatives, chemicals or stimulants. 100%, MONEY BACK GUARANTEE: Noomadic's Indole-3-Carbinol is the highest quality on the market.
Indole-3-carbinol (97%) and Îē-Naphthoflavone (98+%) were obtained from Thermo Scientific(tm) (122190250 and A18543. 06, respectively). BNF was used as a reference compound of activation of AhR signaling. Both compounds were dissolved in DMSO and the I3C compound was used at 1, 5, 10, 20, 40 ΞM. BNF was tested at 1, 5, 10, 20, 40 nM concentrations.
Indole-3-carbinol (I3C) is a natural product contained in vegetables belonging to the Brassicaceae family and has been studied in recent decades for its biological and pharmacological properties. Herein, we will analyze: (1) the biosynthetic processes and synthetic procedures through which I3C and its main derivatives have been obtained; (2) the characteristics that lead to believe that both .
Affiliation. Indole-3-carbinol (I3C) is a bioactive phytochemical abundant in cruciferous vegetables. One of its main in vivo metabolites is 3,3'-diindolylmethane (DIM), formed by the condensation of two molecules of I3C. Both I3C and DIM alter multiple signaling pathways and related molecules controlling diverse cellular events, including .
-preheat oven to 400. -break up bunch broccoli on a cookie sheet. -drizzle with EVOO -sprinkle minced garlic and crushed red pepper. -roast for 15-20 mins. -great tasting I3C.
Indole-3-carbinol (IC3) is a substance that the body produces when it breaks down glucobrassicin. Where do you find glucobrassicin? It's a compound found naturally in cruciferous vegetables like cauliflower and broccoli. You can also find IC3 sold in supplement form.
Numerous in situ studies have implicated indole-3-carbinol, a breakdown product of the glucosinolate indole-3-ylmethylglucosinolate, as one of the phytochemicals with anti-cancer properties. Indole-3-carbinol influences a range of cellular processes, but the mechanisms by which it acts on cancer cells are slowly being revealed.
We have previously investigated CTet, a novel anticancer agent obtained from the broccoli-derived compound indole-3- carbinol (I3C), that shows great anticancer potential in both in vitro and in vivo studies. Here we evaluated the potential of CTet as a chemopreventive agent in aromatase expressing MCF-7/AROM-1 breast cancer cells.
When taken by mouth: Indole-3-carbinol is possibly safe when used in doses up to 400 mg daily for 3-76 months. Side effects might include balance problems, diarrhea, nausea, rash, and tremors.
1. Estrogen Metabolism One of the primary benefits of Indole-3-Carbinol is its ability to influence estrogen metabolism in men. It helps shift estrogen metabolism towards a more favorable pathway known as the 2-hydroxyestrone pathway.
Indole-3-carbinol (I3C) is a bioactive phytochemical abundant in cruciferous vegetables. One of its main in vivo metabolites is 3,3âē-diindolylmethane (DIM), formed by the condensation of two molecules of I3C. Both I3C and DIM alter multiple signaling pathways and related molecules controlling diverse cellular events, including oxidation .
Indole-3-carbinol (I3C, C 9 H 9 N O) is produced by the breakdown of the glucosinolate glucobrassicin, which can be found at relatively high levels in cruciferous vegetables such as broccoli, cabbage, cauliflower, brussels sprouts, collard greens and kale. It is also available in dietary supplements. Indole-3-carbinol is the subject of on-going biomedical research into its possible .
This formulation provides you with several ingredients to help enhance your testosterone: 600mg Ashwagandha 600mg Fenugreek 470 mg ZMA 500 mg Shlajit 250mg Calcium 100 mg Boron 100 mg DIM 100 mg Tongkat ali 40 mg Indole-3-Carbinol 50 mg Astragin KSM-66(tm) (Ashwagandha) (Withania Somnifera)
Shoot for 400mg daily, can be used for long period of time, 3 months on, month off. , etc. Avoid the NOW brand due to the flax component (estrogenic). Originally Posted by Dr. Houser (2) Estrogenic Channeling Agents Indole-3-Carbinol (I3C)
Introduction Metabolism and Bioavailability Biological Activities Effects on biotransformation enzymes Anti-estrogenic activities Modulation of cell-signaling pathways Disease Prevention Cancer Disease Treatment Human papilloma virus infection- related diseases Systemic lupus erythematosus Sources Food Supplements Safety Adverse effects
The most popular bodybuilding message boards! Hi! I am currently taking Myotest which contains I3C but i have read that if you are taking proton pump blockers (which I am) you aren't getting the full benefits of I3C because it needs stomach acid to digest.
Diindolylmethane (DIM, in short) is the principal breakdown product of indole 3-carbinol (I3C), the phytochemical found in cruciferous vegetables like cabbage, cauliflower, broc****, brussel sprouts, kale, collards, mustard greens, radishes, watercress, and turnips.
Results 1 to 15 of 15 Thread: Indole-3-Carbinol Thread Tools Search Thread 10-18-2009, 09:36 PM #1 TheDictionary Registered User Join Date: Apr 2008 Location: United States Age: 34 Posts: 418 Rep Power: 0 Indole-3-Carbinol I know what it's supposed to do, does it work? Any noticeable effects? Any affects after discontinuing usage?
Article Open access Published: 07 February 2024 Indole-3-carbinol (I3C) reduces apoptosis and improves neurological function after cerebral ischemia-reperfusion injury by modulating microglia.