January 02, 2024 17:21 / Last edited by rinagnelpthand1970 7 months ago
Tianeptine sulfate is later developed and improved versions to replace the sodium form. 2. Stability. (sulfate salt is more stable than sodium salt) Both tianeptine sodium and sulfate are stable when protected from light and air. But sodium salt is very hygroscopic to get chunky. While tianeptine sulfate salt contains monohydrate itself, it is . ->
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Midwest USA May 22, 2022 #1 Hello fellow people of earth. I'll cut right to the chase. My friend hooked me up with some ZAZA (tianeptine) and I was just wondering if these capsules are the sulfate or the sodium form? The bottles don't say much but I am surprised to see that one of the bottles 'ZAZA Silver' contains phenibut.
Scottsdale Living What's the right tianeptine sulfate dosage for you? Are you interested in taking tianeptine sulfate? Well, if that's the case, you must be aware of the correct tianeptine.
It only gets worse when you have to take it three times a day. Tianeptine sulfate is soluble and cam be mixed easily with water. * Duration - The effect tianeptine sulfate lasts longer than tianeptine sodium. Tianeptine sulfate is absorbed by the body slowly so its effect is also extended and that means less dosing.
Jan 6, 2023 Messages 121 Jan 6, 2023 #1 If my tianeptine sweet spots are: 130mg (sodium) and 225mg (sulfate) what is the equivalent for free acid? Also, what do these terms really mean (chemically speaking)? TIA MDPV_Psychosis Bluelighter Joined Sep 15, 2006 Messages 2,243 Location Norcal Jan 6, 2023 #2
Tianeptine sulfate is absorbed by the body much more slowly, it is easier to absorbed, the half-time of Tianeptine sulfate is longer than Tianeptine sodium. This means that less frequent administration is required. In order to get same effect with Tianeptine sulfate, the dose of Tianeptine sodium goes 6-7 a day. 4. Water solubility.
While the sulfate salts is improved version of the tianeptine sodium, it is non-hygroscopic,non-clumpy, easier to handle. 2, The Sulfate salts has a better water-solubility, which means the sulfate form has a higher bioavailability . 3, The taste of Sodium salt has been described as "bitter , while the sulfate form has very little taste at all.
Tianeptine is most commonly found in its sodium salt form because it is the only version that is sold by pharmacies and prescribed by doctors. However, the sulfate salt is now also being marketed on nootropic vendor sites, suggested as being superior to the sodium salt, especially with respect to having a longer half-life and duration.
Summary What is already known about this topic? Tianeptine is an antidepressant drug that is not approved by the Food and Drug Administration (FDA). Clinical effects of tianeptine abuse and withdrawal can mimic opioid toxicity and withdrawal. What is added by this report?
"Tianeptine supplements are sometimes labeled as a 'nootropic,' claiming to boost brain function," Dr. Anand notes, "or they might say they treat asthma, pain, opioid use disorder or anxiety . But it's not safe or effective for any of these uses. " You also can't be sure what's actually in tianeptine products.
emmamiah April 14, 2021 2 4 minutes read In the United States, about 40 million Americans struggle with depression. If you're one of those people, you may be looking for some type of relief from the .
Depression and anxiety Tianeptine shows efficacy against serious depressive episodes ( major depression ), comparable to amitriptyline, imipramine and fluoxetine, but with significantly fewer side effects. [18] It was shown to be more effective than maprotiline in a group of people with co-existing depression and anxiety. [10]
Overview Tianeptine is a prescription drug used for depression in some European, Asian, and Latin American countries. It is not approved for use in the US. Tianeptine affects brain chemicals. .
Half-life 2-3 hours. The only version that can be prescribed by a doctor in EU and some other countries under the name of Coaxil or Stablon. The dosing is in the form of 12. 5mg hard tic-tac like seeds, that actually prolong the onset and duration. The recommended dosing is 3x12. 5mg per day. I used to be prescribed 25mg 3x per day.
Overall rating 5. 0. Effectiveness. Ease of Use. Satisfaction. I have been on antidepressants several times in my life and this one is far the best. Results are quick, increases energy, concentration, mood is lifted, and anxiety reduced. Does not cause weight gain and does not decrease libido.
The chemical structure for tianeptine. 1 . is shown below. O O S N Cl OH O . Tianeptine is often encountered in a salt form, such as its sodium or sulfate salt. Pharmacology: Data from preclinical studies show that tianeptine binds to and acts as an agonist at the mu opioid receptor. Additional studies demonstrated that tianeptine has no
Tianeptine sulfate is believed to present some diferences versus tianeptine sodium: it is sold only through the Internet without prescrption, the daily dose is 25mg per day versus 12. 5mg every 8 hours and it might be more potent and long lasting. Those differences were confirmed by the patient after the prescription of tianeptine sodium.
The serum concentration of Tianeptine can be increased when it is combined with Estrone sulfate. . The risk or severity of seizure can be increased when Tianeptine is combined with Sodium phosphate, monobasic. . Lee OY, Kwon JG, Park KS, Lim YJ, Kim TH, Jung SW, Kim JI: Tianeptine vs amitriptyline for the treatment of irritable bowel .
A "dietary ingredient" is a vitamin; mineral; herb or other botanical; amino acid; dietary substance for use by man to supplement the diet by increasing the total dietary intake; or a concentrate,.
Originally believed to be an atypical antidepressant acting at serotonin transporters, tianeptine is now known to also be an atypical agonist at mu-opioid receptors. Its nonmedical use may be increasing amidst the broader context of novel drug and supplement use. Objectives: