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PMID: 24081634 DOI: 10. 1177/0748233713501365 Abstract Boldenone (BOL) is an androgenic steroid that improves the growth and food conversion in food-producing animals. In most countries worldwide, this anabolic steroid is forbidden for human uses and meat production as it was developed for veterinary use. Anabolic androgenic steroids (AAS) are synthetic derivatives of the male testosterone hormone that have been modified to improve their anabolic rather than androgenic activity (Shahidi 2001). The anabolic effects of AAS promote protein synthesis, muscle growth and erythropoiesis (Mottram & George 2000). Hence, AAS are used to enhance strength and durability of canine, equine and human athletes . Anabolic steroids (ABS) boldenone (BL; 1. 1 mg/kg) and stanozolol (ST; 0. 55 mg/kg) were administered i. m. to horses and the plasma samples collected up to 64 days. Anabolic steroids and androgenic steroids (ANS) in plasma were quantified using liquid chromatography-tandem mass spectrometry (LC-MS/MS). The limit of detection of all analytes was . The aim of this study was to assess if the dose and exposure duration of the anabolic androgenic steroids (AAS) boldenone (BOL) and stanazolol (ST) affected memory, anxiety, and social interaction, as well as acetylcholinesterase (AChE) activity and oxidative stress in the cerebral cortex (CC) and hippocampus (HC). Anabolic Agents category. As boldenone may also occur naturally at very low concentrations in the urine, WADA-accredited laboratories apply a specific analysis procedure called carbon isotope ratio mass spectrometry, or GC/C/IRMS, to differentiate between external administration and internal production. Steroid Profiles Equipoise Equipoise (Boldenone Undecylenate) (Boldenone Undecylenate) Boldenone Undecylenate is a testosterone derived anabolic androgenic steroid that is best known by the trade name Equipoise given to it by Squibb in the 1970's. Abstract. The review summarizes current knowledge on the possible illegal use of the anabolic steroid boldenone. The presence of' boldenone and metabolites in different animal species and the possibility of the occurrence of endogenous boldenone and metabolites is assessed, as are the methods of analysis used for detection. Short-term treatment can produce increases in estradiol, dihydrotestosterone, testosterone (total and unbound), and the ratio of dihydrotestosterone to testosterone. When ill-advisedly used to promote growth in boys by administration for some years, oxandrolone caused gynecomastia in a high proportion of subjects treated; 23 of the 33 patients . Equipoise has an anabolic to androgenic ratio of 100:50, compared with testosterone having an even 100:100 ratio. Most steroid users are familiar with the legendary compound Dianabol which EQ shares a virtually identical chemical structure with, but a slight modification allows each one to have a very different effect on the body. Anabolics 101 - Featuring Equipoise ( Boldenone Undecylenate) Description. Equipoise is the most commonly recognized trade name for boldenone undecylenate, an injectable veterinary steroid that exhibits strong anabolic and moderately androgenic properties. The undecylenate ester extends the activity of the drug greatly (the undecylenate ester is only one carbon atom longer than decanoate), so . Determining the origin of anabolic androgenic steroids (AAS) that also are produced endogenously in the human body is a major issue in doping control. In some cases, the presence of nandrolone and boldenone metabolites might result from endogenous production. Pharmacology Pharmacodynamics Like other AAS, boldenone is an agonist of the androgen receptor (AR). [7] The activity of boldenone is mainly anabolic, with a low androgenic potency. Boldenone will increase nitrogen retention, protein synthesis, increases appetite and stimulates the release of erythropoietin in the kidneys. [8] ChemistryA method based on gas chromatography coupled to isotope ratio mass spectrometry (GC/C/IRMS) after a urine sample purification by high performance liquid chromatography (HPLC) permitted to confirm the main synthetic like boldione/boldenone metabolite (17β-hydroxy-5β-androst-1-en-3-one) and boldenone at trace levels (< 5 ng/mL) and then to establi. The anabolic-to-androgenic ratios are favorable for boldenone, but people do not consider boldenone a particularly potent steroid--- possibly due to the low doses that are utilized. Also, boldenone does not cause much water retention--- so many people assume it is not working if they do not put on 10 pounds in one week. #1 Compound:------------------------------Androgenic------Anabolic 1-Testosterone--------------------------100------200 Anabolicum Vister (Quinbolone) (oral Boldenone)--50------100 Anadrol 50 (Oxymetholone)-------------45------320 Anadur (Nandrolone Hexyloxyphenylpropionate)--37-----125 Anatrofin (Stenbolone Acetate)---------107-144-----267-332Figure 4b shows a plot of the ratio of 13 C-testosterone to 12 C-testosterone against time. The ratio stayed essentially around 1 from 10 to 270 h post-administration, suggesting that there was minimal kinetic isotope effect. . Concentration of testosterone, boldenone, 4-estrene-3,17-dione and nandrolone by LC-MS in the positive ESI SRM . Abstract Determining the origin of anabolic androgenic steroids (AAS) that also are produced endogenously in the human body is a major issue in doping control. In some cases, the presence of nandrolone and boldenone metabolites might result from endogenous production. Overview and History of Equipoise. Equipoise is the brand/trade name for the anabolic steroid Boldenone, which is an oil-based injectable anabolic steroid with the Undecylenate ester attached to it for a prolonged release rate and half-life. It is a derivative of Testosterone that retains Testosterone's anabolic strength but exhibits a reduced androgenic effect in comparison. Boldenone Undecylenate (BLD) is a synthetic derivative of testosterone and a widely used anabolic androgenic steroid. The health risk of BLD use as a pharmaceutical or dietary supplement is still underestimated and under-reported. Vitamin C (VC) has been recognized as an antioxidant with prominent hepatorenal protective effects. This study investigated the possible preventive activity of VC . Boldenone (BOLD), an anabolic steroid, is likely to be abused in livestock breeding and in sports. Although some of BOLD metabolites in human urine, such as 5β-adrost-1-en-17β-ol-3-one (BM1), have been detected, investigations on their excretion patterns for both genders are insufficient. Moreover, ...Pharmacodynamics Boldenone undecylenate is a prodrug of boldenone, and hence is an agonist of the androgen receptor. [6] Boldenone has strong anabolic effects and moderate androgenic effects. [6] It also has low estrogenic activity [11] and has little or no progestogenic activity. [6]Abstract Gas chromatography/combustion/isotope ratio mass spectrometry (GC/C/IRMS) can be used to detect the synthetic forms of endogenous anabolic androgenic steroids (EAAS) by comparing the 13 C/ 12 C ratios of the endogenous reference compound to that of the target compound. Boldenone is an anabolic steroid characterized by high anabolic and low androgenic activities. 17β-Boldenone, also called 1-dehydrotestosterone, androsta-1,4-diene-17β-ol-3-1, is a steroid with androgenic activity that differs from 17β-testosterone by only one double bond at the 1 position. . Although the calculated albumin/globulin ratio .
Anabolic Pharmacology: Equipoise - Anabolic Androgenic Steroid Carbon isotope ratios of nandrolone, boldenone, and testosterone . Metabolism of boldione in humans by mass spectrometric . - PubMed Adverse effects of the anabolic steroid, boldenone undecylenate, on . Metabolism study of boldenone in human urine by gas . - PubMed Evaluation of boldenone as a growth promoter in broilers: safety and . Equipoise (Boldenone) - Steroids Profile - Steroidal. com Isolation and enrichment of Boldenone and its main metabolite in . Boldenone - an overview | ScienceDirect Topics Anabolics 101 - Equipoise (boldenone undecylenate) - Muscular Development Frontiers | Boldenone Undecylenate-Mediated Hepatorenal Impairment by . Carbon isotope ratios of nandrolone, boldenone, and testosterone . Physiological and biochemical changes after boldenone injection in . 5 Things Athletes Should Know About Boldenone | USADA Boldenone - Wikipedia Pharmacokinetics of boldenone and stanozolol and the results of . A comparative study of the effect of the dose and exposure duration of . Boldenone undecylenate - Wikipedia Presence and metabolism of the anabolic steroid boldenone in various . Equipoise - steroid. com Anabolic ratio and Androgenic ratio chart - Anabolic Steroid Forums Equipoise Cycle (Boldenone Cycle Guide) | Steroid Cycles Evidence of boldenone, nandrolone, 5(10)‐estrene‐3β‐17α‐diol and 4 .